Sumin Lee

Balancing spatial resolution and proteome depth in LC-MS based spatialproteomics

This study evaluates the trade-off between spatial resolution and proteome depth in spatial proteomics using SLACS, showing that few-cell sampling maintains proteomic information while increasing spatial specificity.

Cryptic disease-prone states in human mesocortical assembloids revealed by multimodal profiling

The paper identifies disease-prone states in human mesocortical assembloids using multimodal profiling, revealing intrinsic susceptibility to neurodegeneration.

Label-free quantitative phenotyping of hepatic stellate cell activation using holotomography with AI-enabled subcellular segmentation

This paper introduces a label-free method using holotomography and AI to quantify hepatic stellate cell activation in live cells, distinguishing quiescent and activated states.

Long-term three-dimensional high-resolution imaging of live unlabeled small intestinal organoids using low-coherence holotomography

This study introduces low-coherence holotomography for long-term live imaging of unlabeled mouse small intestinal organoids, capturing high-resolution morphological details and differentiating viable from non-viable organoids.