Mind the translational gap: human microglia differ from mouse microglia in their regulation of Kv and Kir2.1 channels
Simone Schilling, Jessica Felk, Majed Kikhia, Alice Podestà, Johanna Hintze, Pawel Fidzinski, Martin Holtkamp, Julia Onken, Thomas Sauvigny, Thilo Kalbhenn, Matthias Simon, Helmut Kettenmann, Matthias Endres, Ria Göttert, Karen R. Gertz
The paper compares Kv and Kir2.1 channel activity in human and mouse microglia, finding significant differences in their regulation and functional responses.
bioRxiv · Mar 10, 2026 · PreprintNeuroscience