Syncytial coupling of mid-capillary pericytes underlies seizure-associated electro-metabolic signaling
Mirja grote Lambers, Majed Kikhia, Agustin Liotta, H. Wang, Henrike Planert, Thilo Kalbhenn, Ran Xu, Julia Onken, Thomas Sauvigny, Ulrich‐Wilhelm Thomale, Angela Maria Kaindl, Martin Holtkamp, Pawel Fidzinski, Matthias Simon, Henrik Alle, , Richard Kovács
The paper investigates electrical signaling between mid-capillary pericytes and endothelial cells in the neurovascular unit, showing syncytial coupling and its role in transmitting seizure-associated signals without relying on VGCCs.
bioRxiv · Jun 14, 2026 · PreprintNeuroscience