Inhibition of Soluble Epoxide Hydrolase Ameliorates Cerebral Blood Flow Autoregulation and Cognition in Alzheimer's Disease and Diabetes-Related Dementia Rat Models
Chengyun Tang, Jane J. Border, Huawei Zhang, Andrew Gregory, Shan Bai, Xing Fang, Yedan Liu, Shaoxun Wang, Sung Hee Hwang, Wen‐Jun Gao, Gilbert C. Morgan, Jhania Smith, David Bunn, Cameron Cantwell, Karen M Wagner, , Fan Fan
This study shows that inhibiting soluble epoxide hydrolase (sEH) with TPPU improves cerebral blood flow autoregulation and cognition in Alzheimer's and diabetes-related dementia rat models.
GeroScience · Feb 4, 2025Peer-reviewedMolecular Biology