Quantitative MRI Reveals Bone Marrow Regeneration Following Targeted Marrow Irradiation and Transplantation in a Sickle Cell Disease Model
Malakeh Malekzadeh, Hemendra Ghimire, Ji Eun Lim, Srideshikan Sargur Madabushi, Weidong Hu, Marco Andrea Zampini, Kazuki Fujita, Raghda Fouda, Guy A Storme, Susanta Kumar Hui
This study uses MRI and micro-CT to show that marrow irradiation and transplantation in a sickle cell disease model partially restores bone marrow structure and function.
bioRxiv · Dec 11, 2025 · PreprintBioengineering