Author

Jialin Shang

Cornell University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Annette ChoiiD· 1 shared gary whittaker· 1 shared Hening LiniD· 1 shared J. Christopher FrommeiD· 1 shared Jéssica Caroline Gomes NolliD· 1 shared Kewen PengiD· 1 shared Shamar D. WallaceiD· 1 shared Suryadeep Chakraborty· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperPharmacology & Toxicology

Annette ChoiORCID

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Author profile →

1 paper

Recent·Most cited

Development of GS-441524 Derivatives as Potent SARS-CoV-2 Mac1 Inhibitors via a Direct-to-Biology Approach

Kewen Peng, Suryadeep Chakraborty, Shamar D. Wallace, Jéssica Caroline Gomes Noll, Jialin Shang, Xuan Lu, Annette Choi, gary whittaker, J. Christopher Fromme, Hening Lin

The paper develops potent SARS-CoV-2 Mac1 inhibitors through a direct-to-biology approach, improving the potency of GS-441524 to KP-S54 with IC50 values of 44 nM and 91 nM against SARS-CoV-2 and MERS-CoV Mac1, respectively.

European Journal of Medicinal Chemistry · Aug 28, 2026Peer-reviewedPharmacology & Toxicology