Immune dysregulation in the prostates of C57BL/6Aire-/- mice mirrors that seen in human benign prostatic hyperplasia
Nadia A. Lanman, Meaghan Maureen Broman, Harish Kothandaraman, Gregory M. Cresswell, Gada D. Awdalkreem, Dilinaer Wusiman, Andree K. Kolliegbo, Alexander P. Glaser, Brian T. Helfand, Renee E. Vickman, Jiang Yang, Simon W. Hayward, Timothy L. Ratliff
This paper develops a mouse model of chronic prostatic inflammation that mirrors human BPH by showing similar immune and fibroblast features identified through scRNA-seq.
The Journal of Pathology · Jul 8, 2026Peer-reviewedImmunology