Author

Jiayi Pei

University Medical Center Utrecht

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:dimensionality reduction· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Alain van MiliD· 1 shared Aryan VinkiD· 1 shared Boudewijn M.T. BurgeringiD· 1 shared C. Snijders BlokiD· 1 shared Caroline ChengiD· 1 shared Dries A. M. Feyen· 1 shared Ema Nagyova· 1 shared Folkert Wouter AsselbergsiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

Alain van MilORCID

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2 papers

Recent·Most cited

Statistical Integration of Two Omics Datasets Using GO2PLS

Z. Gu, Said el Bouhaddani, Jiayi Pei, Jeanine J. Houwing‐Duistermaat, Hae‐Won Uh

This paper introduces GO2PLS, a method that integrates two omics datasets with sparsity and group structure, improving feature selection and interpretability in biological systems.

BMC Bioinformatics · Mar 18, 2021Peer-reviewedBioinformatics

Transcriptional regulation profiling reveals disrupted lipid metabolism in failing hearts with a pathogenic phospholamban mutation

Jiayi Pei, Renée G. C. Maas, Ema Nagyova, Johannes M.I.H. Gho, C. Snijders Blok, Iris van Adrichem, Jorg J. A. Calis, René van Es, Shahrzad Sepehrkhouy, Dries A. M. Feyen, Noortje A. M. van den Dungen, Nico R. Lansu, Nicolaas de Jonge, Hester M. den Ruijter, Manon M. H. Huibers, , Magdaléna Harakaľová

The paper investigates epigenetic and transcriptional changes in PLN R14del cardiomyopathy, identifying disrupted lipid metabolism and altered gene regulation.

bioRxiv · Nov 30, 2020 · PreprintGenomics