Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans
Daniel Martins, Ndaba Mazibuko, Fernando O. Zelaya, S. Vasilakopoulou, Joanna Loveridge, Alice E. Oates, Stefanos Maltezos, Mitul Ashok Mehta, Stephen J. Wastling, Matthew A. Howard, Grainne Mary McAlonan, Declan Murphy, Steven Williams, Aikaterini Fotopoulou, Uwe Schuschnig, Yannis Paloyelis
This study compares intranasal and intravenous oxytocin administration effects on regional cerebral blood flow, showing systemic OT increases drive amygdala perfusion changes and validating intranasal targeting of specific brain regions.
Nature Communications · Mar 3, 2020Peer-reviewedNeuroscience