Matthew A. Howard

Test-retest reliability of sensorimotor activity measured with spinal cord fMRI

This study evaluates the test-retest reliability of spinal cord fMRI during sensorimotor tasks, finding poor-to-fair reliability despite consistent task performance and signal quality.

Susceptibility-matched padding improves the quality of cervical and lumbar spinal fMRI

This study evaluates susceptibility-matched padding's impact on spinal fMRI quality, finding improved B0 field homogeneity and functional image metrics in cervical and lumbar spinal cord scans.

EPISeg: Automated segmentation of the spinal cord on echo planar images using open-access multi-center data

The paper introduces EPISeg, a deep learning model for automated spinal cord segmentation on gradient-echo EPI data, showing improved performance over existing methods.

Normative Modelling of Molecular-based Functional Neurocircuits Captures Clinical Heterogeneity Transdiagnostically in Neuropsychiatric Patients

The paper uses REACT and normative modelling to analyze functional neurocircuits in neuropsychiatric patients, revealing transdiagnostic deviations in neurotransmitter systems and symptom overlaps.

A novel implementation of spinal fMRI demonstrates segmental organisation of functionally connected networks in the cervical spinal cord: A test-retest reliability study

This paper introduces a novel spinal fMRI method to study functional connectivity in the cervical spinal cord, finding mixed test-retest reliability but consistent spatial organization across sessions.

The Effects of Propofol Anaesthesia on Molecular-enriched Networks During Resting-state and Naturalistic Stimulation

This study uses REACT to examine how propofol affects neurotransmission-related functional connectivity during rest and naturalistic stimulation, revealing changes in GABAergic, noradrenergic, and cholinergic networks.

A candidate neuroimaging biomarker for detection of neurotransmission-related functional alterations and prediction of pharmacological analgesic response in chronic pain

This paper identifies neurotransmission-related functional connectivity biomarkers in chronic pain patients and shows their predictive value for analgesic response to duloxetine.

Transcriptional and cellular signatures of cortical morphometric similarity remodelling in chronic pain

This study identifies cortical morphometric similarity remodelling in chronic pain and links it to transcriptomic changes in glial and neuronal genes across multiple pain syndromes.

Sustained perturbation in functional connectivity induced by cold pain

This study examines functional connectivity changes during and after cold pain in healthy volunteers, finding persistent alterations related to reported pain intensity.

Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans

This study compares intranasal and intravenous oxytocin administration effects on regional cerebral blood flow, showing systemic OT increases drive amygdala perfusion changes and validating intranasal targeting of specific brain regions.