Persistent increases of PKMζ in memory-activated neurons trace LTP maintenance during spatial long-term memory storage
Changchi Hsieh, Panayiotis Tsokas, Alejandro Borja Grau-Perales, Edith Lesburguères, Joseph Bukai, K. L. Khanna, Joelle Chorny, Ain Chung, Claudia Jou, Nesha S. Burghardt, Christine Ann Denny, Rafael E. Flores‐Obando, Benjamin Rush Hartley, Laura Melissa Rodriguez-Valencia, Alejandro Ivan Hernandez, , Todd Charlton Sacktor
The paper shows that persistent PKMζ increases in specific hippocampal neurons during LTP maintenance and spatial memory storage, indicating its role in long-term memory.
European Journal of Neuroscience · Feb 7, 2021Peer-reviewedNeuroscience