Author

Johanna Lepland

Erasmus MC

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Akin Bucakci· 1 shared Anne de Snaijer· 1 shared Els ManselliD· 1 shared Eric M. BindelsiD· 1 shared Gregory van BeekiD· 1 shared Marc H.G.P. RaaijmakersiD· 1 shared Tariq EnveriD· 1 shared Tim V. D. van TienhoveniD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Akin Bucakci

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1 paper

Recent·Most cited

Targeting mitochondria mitigates chemotherapy-induced bone marrow dysfunction

Tim V. D. van Tienhoven, Johanna Lepland, Anne de Snaijer, Akin Bucakci, Wout Maaskant, Gregory van Beek, Eric M. Bindels, Marc H.G.P. Raaijmakers, Tariq Enver, Valgarður Sigurðsson, Els Mansell

This paper shows that chemotherapy causes long-term bone marrow dysfunction by impairing hematopoietic stem cells, which can be reversed by mitochondrial-targeted treatment.

bioRxiv · Jul 18, 2025 · PreprintCell Biology