Author

John Bruce

University of Strathclyde

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Microbiology· 1

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Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Andrew J. Collis· 1 shared Angelika B. KiepasiD· 1 shared Barrie M. WilkinsoniD· 1 shared Benjamin D. HuckleiD· 1 shared Daniel E. LarcombeiD· 1 shared Iain S. HunteriD· 1 shared James T CroxfordiD· 1 shared John MunnochiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Andrew J. Collis

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1 paper

Recent·Most cited

Genome evolution during the domestication of an antibiotic-producing Streptomyces strain

John Munnoch, Daniel E. Larcombe, Rebecca E. McHugh, John Bruce, Kirsty Robb, James T Croxford, Angelika B. Kiepas, Juan Pablo Gomez‐Escribano, Nicola A. Crowhurst, Andrew J. Collis, Steven G. Kendrew, Benjamin D. Huckle, Barrie M. Wilkinson, Iain S. Hunter, Paul A. Hoskisson

This study analyzes genomic changes in Streptomyces clavuligerus strains during domestication, showing how mutations and rearrangements enhance antibiotic production while reducing metabolic flexibility.

bioRxiv · Aug 28, 2026 · PreprintMicrobiology