Paul A. Hoskisson

This study shows how a bacterial Rhesus transporter modifies a conserved ammonium pore to function as a reversible nitrogen valve through specific residue changes.

This study determines the structure and function of NeRh50, a Rh-family protein in Nitrosomonas europaea, revealing lipid associations and divergent ammonium transport properties compared to canonical Amt proteins.

This study analyzes genomic changes in Streptomyces clavuligerus strains during domestication, showing how mutations and rearrangements enhance antibiotic production while reducing metabolic flexibility.

This study creates a genome-scale metabolic model atlas for Streptococcus suis, revealing lineage-specific metabolic differences and identifying potential antimicrobial targets.

The paper identifies 645 amylases and amylase inhibitors in 295 Streptomyces strains, providing a foundation for engineering inhibitor-resistant enzymes for sustainable starch-based fermentations.

This study tracks adaptive radiation in Streptomyces over 3000 generations, showing parallel loss of sporulation, morphological changes, and metabolic diversification under relaxed selection.

This study develops a silicone elastomer colonization model to investigate C. albicans and S. aureus biofilm formation on medical devices, revealing morphological differences based on C. albicans cell morphotypes.

This study quantifies oxygen gradients in E. coli biofilm transport channels using three sensing methods, revealing anoxic conditions that challenge previous assumptions about channel openness.

This study shows that 16S rRNA phylogeny and clustering are unreliable for classifying Streptomyces species, as they often conflict with whole-genome-based taxonomy.

The paper reports the genome sequence of Streptomyces goldiniensis ATCC 21386, which produces the polyketide aurodox, and identifies biosynthetic gene clusters.