John Munnoch

Genome evolution during the domestication of an antibiotic-producing Streptomyces strain

This study analyzes genomic changes in Streptomyces clavuligerus strains during domestication, showing how mutations and rearrangements enhance antibiotic production while reducing metabolic flexibility.

Genome-scale metabolic model atlas of the zoonotic pathogen Streptococcus suis

This study creates a genome-scale metabolic model atlas for Streptococcus suis, revealing lineage-specific metabolic differences and identifying potential antimicrobial targets.

Adaptive radiation during long-term experimental evolution of the multicellular bacterium, Streptomyces

This study tracks adaptive radiation in Streptomyces over 3000 generations, showing parallel loss of sporulation, morphological changes, and metabolic diversification under relaxed selection.

Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386

The paper reports the genome sequence of Streptomyces goldiniensis ATCC 21386, which produces the polyketide aurodox, and identifies biosynthetic gene clusters.