Author

John C. Silbereis

Biogen (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

Akemi ShibataiD· 1 shared Andrew G. CapacciiD· 1 shared Claire M. MetrickiD· 1 shared Daniel FranjiciD· 1 shared David AndrijevićiD· 1 shared Dennis Cherry· 1 shared Devippriya Esakkimuthu· 1 shared Forrest O. GuldeniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Akemi ShibataORCID

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Author profile →

2 papers

Recent·Most cited

GPR17 structure and agonism with small molecules and oxysterols

Claire M. Metrick, Lu Zhang, Maria Hercher, Greg J. Dodge, Dennis Cherry, Jorge Vera Rebollar, Margot Brickelmaier, Jing Wang, Jeffrey G. Martin, Xiaoping L. Hronowski, Melissa Kemp, Andrew G. Capacci, Joseph W. Arndt, Laura F. Silvian, Karen S. Conrad, John C. Silbereis

This study presents cryo-EM structures of GPR17 with ligands and shows orthosteric and allosteric binding mechanisms, suggesting alternative approaches for drug discovery.

bioRxiv · Nov 26, 2025 · PreprintBiochemistry

Molecular Specification of Claustro-Amygdalar and Paleocortical Neurons and Connectivity

Navjot Kaur, Rothem Kovner, Forrest O. Gulden, Mihovil Pletikos, David Andrijević, Tianjia Zhu, John C. Silbereis, Shaojie Ma, Nikkita Salla, Xabier de Martin, Thomas Klarić, Yuting Liu, Akemi Shibata, Daniel Franjic, Hyesun Cho, , Nenad Šestan

This study identifies SOX4, SOX11, and TFAP2D as critical regulators of ventropallial excitatory neuron development and PFC connectivity in mice, with conserved roles in humans.

bioRxiv · Oct 20, 2024 · PreprintNeuroscience