Decreased Mitochondrial Bioenergetics and Function Define a Distinct Metabolic Phenotype in Healthy Sedentary Individuals Detectable Through Non-Invasive CPET
Iñigo San-Millán, Janel L. Martinez, Genevieve C. Sparagna, Angelo D’Alessandro, Davide Stefanoni, Travis G. Nemkov, John Hill
This study identifies a distinct mitochondrial metabolic phenotype in sedentary individuals using non-invasive CPET and finds reduced mitochondrial function and bioenergetics compared to active individuals.
Clinical bioenergetics · Jun 25, 2026Peer-reviewedBiochemistry