Author

John Horton

Duke University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:plant (other)· 1

Frequent Co-Authors

Raluca GordâniD· 2 shared Yuning ZhangiD· 2 shared Alan S Brown· 1 shared Dan LeehriD· 1 shared Gabrielle A. JoslingiD· 1 shared Hilmar LappiD· 1 shared J.L. Schipper· 1 shared Jingkang Zhao· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenomics

Raluca GordânORCID

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2 papers

Recent·Most cited

DNA sequence context and the chromatin landscape differentiate sequence-specific transcription factor binding in the human malaria parasite, Plasmodium falciparum

Victoria Ann Bonnell, Yuning Zhang, Alan S Brown, John Horton, Gabrielle A. Josling, Tsu-Pei Chiu, Remo Rohs, Shaun Mahony, Raluca Gordân, Manuel Llinás

The paper investigates how DNA sequence and chromatin context influence transcription factor binding in Plasmodium falciparum, showing that both factors contribute to differential binding site selection.

Nucleic Acids Research · Jun 27, 2024Peer-reviewedGenomics

Intrinsic specificity differences between transcription factor paralogs partly explain their differential in vivo binding

Ning Shen, Jingkang Zhao, J.L. Schipper, Yuning Zhang, Tristan Bepler, Dan Leehr, John Bradley, John Horton, Hilmar Lapp, Raluca Gordân

The paper identifies intrinsic DNA-binding specificity differences between transcription factor paralogs that partly explain their distinct genomic binding patterns.

Cell Systems · Mar 28, 2018Peer-reviewedGenomics