Author

Ning Shen

Duke University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron N. Chang· 1 shared Alan Robertson· 1 shared Angela M. CacaceiD· 1 shared Anthony Accorsi· 1 shared Dan LeehriD· 1 shared Diego CadavidiD· 1 shared Erin Valentine· 1 shared Hilmar LappiD· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Aaron N. Chang

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2 papers

Recent·Most cited

P38α Regulates Expression of DUX4 in Facioscapulohumeral Muscular Dystrophy

Luis Alejandro Rojas, Erin Valentine, Anthony Accorsi, Joseph Maglio, Ning Shen, Alan Robertson, Steven L. Kazmirski, Peter B. Rahl, Rabi Tawil, Diego Cadavid, Lorin A. Thompson, Lucienne V. Ronco, Aaron N. Chang, Angela M. Cacace, Owen B. Wallace

This study identifies p38 as a regulator of DUX4 expression in FSHD, showing that p38 inhibitors reduce DUX4 and cell death in patient-derived myotubes.

Journal of Pharmacology and Experimental Therapeutics · Jun 23, 2020Peer-reviewedDevelopmental Biology

Intrinsic specificity differences between transcription factor paralogs partly explain their differential in vivo binding

Ning Shen, Jingkang Zhao, J.L. Schipper, Yuning Zhang, Tristan Bepler, Dan Leehr, John Bradley, John Horton, Hilmar Lapp, Raluca Gordân

The paper identifies intrinsic DNA-binding specificity differences between transcription factor paralogs that partly explain their distinct genomic binding patterns.

Cell Systems · Mar 28, 2018Peer-reviewedGenomics