Author

Gabrielle A. Josling

Pennsylvania State UniversityORCID 0000-0001-6411-7812Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Manuel LlinásiD· 3 shared Timothy J. RusselliD· 2 shared Alan S Brown· 1 shared C. Denise OkaforiD· 1 shared Charisse Flerida A. PasajeiD· 1 shared Erandi K. De Silva· 1 shared Francisco‐Javier GamoiD· 1 shared Gianni PanagiotouiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersGenomics

Manuel LlinásORCID

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3 papers

Recent·Most cited

GenomicsNucleic Acids ResearchPeer-reviewedJun 27, 2024

DNA sequence context and the chromatin landscape differentiate sequence-specific transcription factor binding in the human malaria parasite, Plasmodium falciparum

Victoria Ann Bonnell, Yuning Zhang, Alan S Brown…·Manuel Llinás

The paper investigates how DNA sequence and chromatin context influence transcription factor binding in Plasmodium falciparum, showing that both factors contribute to differential binding site selection.

15 citations

plant (other)ChIP-seq

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Molecular BiologybioRxivPreprintApr 5, 2022

Identification of Antimalarial Compounds that Inhibit Apicomplexan AP2 Proteins in the Human Malaria Parasite Plasmodium falciparum

Timothy J. Russell, Erandi K. De Silva, Valerie M. Crowley…·Manuel Llinás

The paper identifies antimalarial compounds that inhibit ApiAP2 proteins in Plasmodium falciparum by screening small molecules against the AP2-EXP domain and validating their effects on parasite gene regulation and growth.

1 citation

humanprotein structure

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MicrobiologybioRxivPreprintFeb 8, 2019

Regulation of sexual differentiation is linked to invasion in malaria parasites

Gabrielle A. Josling, Jarrett Venezia, Lindsey Orchard…·Manuel Llinás

The paper shows PfAP2-G activates gametocyte genes and also promotes red blood cell invasion genes, linking sexual differentiation to invasion in malaria parasites.

DOI 10.1101/533877

humanmouse

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