Author

John M. Crespo

Temple University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Amanda B. MuiriD· 2 shared Anne Staub· 2 shared Annie D. FulleriD· 2 shared Jazmyne L. JacksoniD· 2 shared Kelly A. WhelaniD· 2 shared Melanie A. RuffneriD· 2 shared Aissata Balde· 1 shared Alena KlochkovaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCell Biology

Amanda B. MuirORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

NIX-associated mitochondrial remodeling contributes to esophageal epithelial differentiation

No’ad Shanas, Aissata Balde, Annie D. Fuller, Jazmyne L. Jackson, Anne Staub, John M. Crespo, William Nazario-Lugo, Alexander Tufano, Nicholas M. McDonald, Andres Klein Szanto, Kathy Qi Cai, Melanie A. Ruffner, Amanda B. Muir, Zachary Reichenbach, Kelly A. Whelan

This study shows that NIX-mediated mitochondrial remodeling is essential for esophageal epithelial differentiation and that its disruption may contribute to eosinophilic esophagitis.

bioRxiv · Sep 18, 2026 · PreprintCell Biology

Interleukin-13-mediated alterations in esophageal epithelial mitochondria contribute to tissue remodeling in eosinophilic esophagitis

Jazmyne L. Jackson, Reshu Saxena, Mary Grace Murray, Anne Staub, Alena Klochkova, Travis H. Bordner, Courtney Worrell, Annie D. Fuller, John M. Crespo, Andres J. Klein–Szanto, John W. Elrod, Tatiana A. Karakasheva, Melanie A. Ruffner, Amanda B. Muir, Kelly A. Whelan

This study identifies IL-13 as a driver of increased mitochondrial mass in esophageal keratinocytes, impairing squamous cell differentiation and contributing to eosinophilic esophagitis.

bioRxiv · Apr 2, 2025 · PreprintMolecular Biology