Author

John M. Leong

Primary ORCID profile (0000-0003-0240-6402 · 5 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

John M. LeongiD5 papers · Tufts University

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alenka Lovy· 1 shared Andrew Camilli· 1 shared Elsa N. Bou GhanemiD· 1 shared Guillermo Arroyo· 1 shared Joana M. PereiraiD· 1 shared Manmeet BhallaiD· 1 shared Michael J. Pereira· 1 shared Nick Lee· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Alenka Lovy

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1 paper

Recent·Most cited

Streptococcus pneumoniae infection of lung epithelial cells induces internalization of surface GPI-anchored proteins through pneumolysin-mediated activation of host Rho GTPases

Nick Lee, Manmeet Bhalla, Joana M. Pereira, Stacie Clark, Sara E. Roggensack, Alenka Lovy, Michael J. Pereira, Guillermo Arroyo, Walter Adams, Andrew Camilli, Rodney K. Tweten, John M. Leong, Sandra Sousa, Elsa N. Bou Ghanem

This study shows that pneumolysin from Streptococcus pneumoniae causes internalization of GPI-anchored proteins in lung epithelial cells via Rho GTPase activation, reducing cell death and membrane damage.

bioRxiv · Apr 17, 2024 · PreprintMicrobiology