Author

John W.S. Brown

James Hutton Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Craig G. SimpsoniD· 2 shared Juan Carlos EntizneiD· 2 shared Runxuan ZhangiD· 2 shared Alois SchweighoferiD· 1 shared Andrea BartaiD· 1 shared Armin FuchsiD· 1 shared Christian MeyeriD· 1 shared Cristiane P. G. CalixtoiD· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersMolecular Biology

Craig G. SimpsonORCID

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Author profile →

3 papers

Recent·Most cited

TranSuite: a software suite for accurate translation and characterization of transcripts

Juan Carlos Entizne, Wenbin Guo, Cristiane P. G. Calixto, Mark Spensley, Nikoleta A. Τzioutziou, Runxuan Zhang, John W.S. Brown

TranSuite improves transcript translation accuracy by identifying correct ORFs and distinguishing between protein-coding and NMD substrates in Arabidopsis transcriptomes.

bioRxiv · Dec 15, 2020 · PreprintBioinformatics

Nonsense mediated RNA decay factor UPF1 is critical for post-transcriptional and translational gene regulation in Arabidopsis

Vivek K. Raxwal, Craig G. Simpson, Jiradet Gloggnitzer, Juan Carlos Entizne, Wenbin Guo, Runxuan Zhang, John W.S. Brown, Karel Říha

This study shows that UPF1 is essential for post-transcriptional and translational regulation in Arabidopsis, affecting alternative splicing, translation, and immune receptor activation.

The Plant Cell · Jul 14, 2020Peer-reviewedMolecular Biology

Light remote control of alternative splicing in roots through TOR kinase

Stefan Riegler, Lucas Servi, Armin Fuchs, Micaela A. Godoy Herz, M. Guillermina Kubaczka, Peter Venhuizen, Alois Schweighofer, Craig G. Simpson, John W.S. Brown, Christian Meyer, Maria Kalyna, Andrea Barta, Ezequiel Petrillo

The paper shows that sugars act as mobile signals controlling alternative splicing in roots through the TOR kinase pathway, with mitochondria playing a key role in this process.

bioRxiv · Dec 5, 2018 · PreprintMolecular Biology