Author

Ramachandran Murali

Cedars-Sinai Medical CenterORCID 0000-0002-8384-2793Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Madhusudhanarao KatikiiD· 2 shared Ambart E. CovarrubiasiD· 1 shared Anders Hayden BergiD· 1 shared Bongha ShiniD· 1 shared Dnyaneshwar Kalyane· 1 shared Hongqiang Wang· 1 shared Jeremy David RudnickiD· 1 shared John Yu· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Madhusudhanarao KatikiORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 8, 2026

Ligand stabilization enables physiological GITR signaling and antitumor immunity

Tesfahun Dessale Admasu, Keerthi Caroline Sadanala, Dnyaneshwar Kalyane…·John Yu

This study shows that stabilizing the GITRL ligand enhances antitumor immunity by enabling physiological signaling between APCs and T cells, unlike receptor-targeted antibodies.

DOI 10.64898/2026.05.04.722444

humanmouse

ImmunologyNature CommunicationsPeer-reviewedJan 8, 2026

Butyrophilin 2A2 promotes T cell immunoregulation by enhancing CD45 phosphatase activity within the immune synapse

Shafat Ali, Anders Hayden Berg, Michifumi Yamashita…·S. Ananth Karumanchi

This study identifies BTN2A2 as a CD45RO ligand that enhances CD45 phosphatase activity, promoting Treg expansion and reducing Th17 cells, thereby ameliorating autoimmunity in mice and humans.

1 citation

mousehuman