Structural basis of gap-filling DNA synthesis in the nucleosome by DNA Polymerase β
Tyler Weaver, Benjamin J. Ryan, Spencer H. Thompson, Adil S. Hussen, Jonah J. Spencer, Zhen Xu, Nicholas Schnicker, Bret Freudenthal
This study determines the structural and kinetic mechanism of DNA Polymerase β processing 1-nt gaps in the nucleosome during DNA repair.
Nature Communications · Mar 17, 2025Peer-reviewedBiochemistry