RNA G-quadruplexes mediate cooperativity in HNRNPH binding and splicing regulation
Kerstin Tretow, Mario Keller, Mikhail V. Mesitov, Miona Ćorović, Mirko Brueggemann, Jonas Busam, Farica Zhuang, Nadine Körtel, Nicolás Melchior, Anke Busch, Simon Braun, Nadja Hellmann, Heike Hänel, Pol Basenius, S. Strand, , Kathi Zarnack
The paper investigates how RNA G-quadruplexes enable cooperative binding of HNRNPH and regulate splicing, showing clinical relevance in breast cancer.
bioRxiv · Mar 3, 2026 · PreprintMolecular Biology