Nadine Körtel

Alternative splicing switches human Musashi-2 between cytoplasmic and nuclear regulatory functions

This study identifies an alternative splicing event in MSI2 that determines its subcellular localization and regulatory function.

RNA G-quadruplexes mediate cooperativity in HNRNPH binding and splicing regulation

The paper investigates how RNA G-quadruplexes enable cooperative binding of HNRNPH and regulate splicing, showing clinical relevance in breast cancer.

Microbial iCLIP2: Enhanced mapping of RNA-Protein interaction by promoting protein and RNA stability

This study develops a microbial iCLIP2 protocol to identify RNA-protein interactions in fungi, revealing Rrm4 binds mitochondrial mRNA stop codons.

Comparative analysis of 43 distinct RNA modifications by nanopore tRNA sequencing

This study demonstrates the use of updated nanopore sequencing to characterize 43 RNA modifications in tRNAs, including mitochondrial and viral tRNAs, and provides best practices for future research.

Deep and accurate detection of m6A RNA modifications using miCLIP2 and m6Aboost machine learning

The paper improves m6A RNA modification detection using miCLIP2 and m6Aboost, identifying thousands of high-confidence sites in human and mouse cells without requiring Mettl3 depletion.