Friederike Schmid

This study shows that kinase-phosphatase cycles drive self-sustained oscillations in TDP-43 condensates through differential recruitment and slow redistribution of enzymes.

This study shows how different domains of TDP-43 interact to control phase separation and condensate dynamics through simulations and experiments.

This study shows phosphorylation of TDP-43's low-complexity domain shifts its self-assembly from macrophase separation to micellization, potentially protecting against pathological aggregation.

The paper investigates how RNA G-quadruplexes enable cooperative binding of HNRNPH and regulate splicing, showing clinical relevance in breast cancer.

The paper uses MD simulations to study helical stability in polyXY sequences at IDR boundaries, finding they form dynamic helices that may aid in protein flexibility.

This study investigates RNA polymerase II condensates in C. elegans using simulations and experiments, showing they exhibit LCST behavior and form distinct phases during transcription.