NitrOFF: An engineered fluorescent biosensor to illuminate nitrate transport in living cells
Mariah A. Cook, Jonathan D. Smailys, Ke Ji, Shelby M. Phelps, Jasmine N. Tutol, Wantae Kim, Whitney S. Y. Ong, Weicheng Peng, Caden Maydew, Yan Zhang, Sheel C. Dodani
The paper introduces NitrOFF, a fluorescent biosensor for real-time nitrate detection in mammalian cells, showing it responds to nitrate with a turn-off fluorescence mechanism.
Angewandte Chemie International Edition · Aug 26, 2025Peer-reviewedBiochemistry