Analysis of lifespan across Diversity Outbred mouse studies identifies multiple longevity-associated loci
Martin N. Mullis, Kevin M. Wright, Anil Raj, Daniel M. Gatti, Peter C. Reifsnyder, Kevin Flurkey, Jonathan R. Archer, Laura L. Robinson, Andrea Di Francesco, Karen L. Svenson, Ron Korstanje, David E. Harrison, J. Graham Ruby, Gary A. Churchill
This study identifies six longevity-associated loci in Diversity Outbred mice through a genetic meta-analysis of lifespan data from three studies, explaining over half of the heritable variation in lifespan.
Genetics · May 6, 2025Peer-reviewedGenetics