Author

David E. Harrison

Jackson LaboratoryORCID 0000-0003-2298-0954Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1 Approach:matrix factorization· 1

Frequent Co-Authors

Randy StrongiD· 2 shared Adrian MolièreiD· 1 shared Alexander TyshkovskiyiD· 1 shared Alibek MoldakozhayeviD· 1 shared Amandeep BajwaiD· 1 shared Anastasiya VladimirovaiD· 1 shared Andrea Di FrancescoiD· 1 shared Anil RajiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersGenetics

Randy StrongORCID

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3 papers

Recent·Most cited

GeneticsNaturePeer-reviewedApr 22, 2026

Genetic Modulation of Lifespan: Dynamic Effects, Sex Differences, and Body Weight Trade-offs

Danny Arends, David George Ashbrook, Suheeta Roy…·Robert W. Williams

This study identifies genetic loci affecting lifespan dynamics, sex differences, and body weight trade-offs in mice using an actuarial approach.

3 citations

mousestatistical model

𝕏 PostBluesky

GeneticsGeneticsPeer-reviewedMay 6, 2025

Analysis of lifespan across Diversity Outbred mouse studies identifies multiple longevity-associated loci

Martin N. Mullis, Kevin M. Wright, Anil Raj…·Gary A. Churchill

This study identifies six longevity-associated loci in Diversity Outbred mice through a genetic meta-analysis of lifespan data from three studies, explaining over half of the heritable variation in lifespan.

4 citations

mousestatistical model

𝕏 PostBluesky

Systems BiologybioRxivPreprintJul 4, 2024

Transcriptomic Hallmarks of Mortality Reveal Universal and Specific Mechanisms of Aging, Chronic Disease, and Rejuvenation

Alexander Tyshkovskiy, Daria Kholdina, Kejun Ying…·Vadim N. Gladyshev

This study identifies transcriptomic biomarkers of mortality across species and models, revealing common aging mechanisms and rejuvenation signatures.

27 citations

mousebulk RNA-seq

𝕏 PostBluesky