J. Graham Ruby

The paper identifies AP-1's role in regulating distinct ECM programs during lung development and fibrosis, showing its potential as a therapeutic target.

The paper uses genetic correlation analysis in DO mice to identify QTL and candidate genes linked to age-related pathologies.

The paper analyzes genetic diversity in naked mole-rats from Kenya and Ethiopia using whole-genome sequencing and a chromosome-scale genome assembly, revealing unexpected genetic divergence patterns.

This study shows that substrate stiffness affects WI-38 cell proliferation and growth arrest pathways, with soft substrates inducing a unique G1 transcriptional state that is reversed by hTERT expression.

This study identifies six longevity-associated loci in Diversity Outbred mice through a genetic meta-analysis of lifespan data from three studies, explaining over half of the heritable variation in lifespan.