STEER-seq: a recombinase based platform for pooled multimodal single-cell perturbation screening
Valentina Migliori, Chenqu Suo, Olli Dufva, Ivan Gyulev, Krzysztof Polański, Vasiliki Symeonidou, Geraldine Rodschinka, Ioannis Sarropoulos, Sho Iwama, Alexander S. Steemers, Aleksander M. Gontarczyk, Hayden Powell, Ana-Maria Cujba, Jong-Eun Sebastiaan Park, Mathew J. Garnett, , Andrew R Bassett
STEER-seq enables pooled single-cell perturbation screening in hiPSCs by using defined genomic integration and barcode tracking to study transcription factor effects on cell identity.
bioRxiv · Oct 9, 2026 · PreprintGenomics