Author

Jose L. Alejo

St. Jude Children's Research Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Aaron E. EngelhartiD· 2 shared Katarzyna P. AdamalaiD· 2 shared Alanna SchepartziD· 1 shared Angelin Prasad· 1 shared Dylan J. GirodatiD· 1 shared Evan M. KalbiD· 1 shared Isaac J. KnudsoniD· 1 shared Jessica A. WilliiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

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10 top collaborators · 33 mutual co-author links

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2 shared papersSynthetic Biology

Aaron E. EngelhartORCID

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2 papers

Recent·Most cited

High yield, low magnesium flexizyme reactions in a water-ice eutectic phase

Joshua A. Davisson, Jose L. Alejo, Mace Blank, Evan M. Kalb, Angelin Prasad, Isaac J. Knudson, Alanna Schepartz, Aaron E. Engelhart, Katarzyna P. Adamala

This paper presents a method for high-yield, low magnesium flexizyme reactions in a water-ice eutectic phase, improving product stability and reducing Mg(II) carryover.

Biochemistry · Aug 20, 2025Peer-reviewedSynthetic Biology

Alternate conformational trajectories in protein synthesis

Jose L. Alejo, Dylan J. Girodat, Michael J. Hammerling, Jessica A. Willi, Michael C. Jewett, Aaron E. Engelhart, Katarzyna P. Adamala

The paper identifies alternate conformational pathways in ribosome translocation by combining directed evolution and molecular dynamics simulations, revealing diverse kinetic and structural dynamics.

bioRxiv · Apr 3, 2024 · PreprintSynthetic Biology