Author

Michael J. Hammerling

Northwestern UniversityORCID 0000-0002-0499-6795Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Michael C. JewettiD· 2 shared Aaron E. EngelhartiD· 1 shared Brian R. Fritz· 1 shared Danielle J. Yoesep· 1 shared Do Soon KimiD· 1 shared Dylan J. GirodatiD· 1 shared Erik D. Carlson· 1 shared Jessica A. WilliiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSynthetic Biology

Michael C. JewettORCID

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2 papers

Recent·Most cited

Alternate conformational trajectories in protein synthesis

Jose L. Alejo, Dylan J. Girodat, Michael J. Hammerling, Jessica A. Willi, Michael C. Jewett, Aaron E. Engelhart, Katarzyna P. Adamala

The paper identifies alternate conformational pathways in ribosome translocation by combining directed evolution and molecular dynamics simulations, revealing diverse kinetic and structural dynamics.

bioRxiv · Apr 3, 2024 · PreprintSynthetic Biology

In vitro ribosome synthesis and evolution through ribosome display

Michael J. Hammerling, Brian R. Fritz, Danielle J. Yoesep, Do Soon Kim, Erik D. Carlson, Michael C. Jewett

This study develops an in vitro method for ribosome synthesis and evolution called RISE, demonstrating its ability to select for ribosome variants resistant to clindamycin and revealing positive epistasis in successful genotypes.

Nature Communications · Feb 28, 2020Peer-reviewedSynthetic Biology