Author

Joseph Lederer

University of Illinois Urbana-Champaign

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Christopher B. BrookeiD· 2 shared Elizabeth A. ThayeriD· 2 shared Joel Rivera-CardonaiD· 2 shared Nicholas C. WuiD· 2 shared Qi Wen TeoiD· 2 shared Sergei MasloviD· 2 shared Tarun MahajaniD· 2 shared Cera A. McDonaldiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSystems Biology

Christopher B. BrookeORCID

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2 papers

Recent·Most cited

Single-cell heterogeneity in interferon induction potential is heritable and governed by variation in cell state

Elizabeth A. Thayer, Gabriela Shipman, Joel Rivera-Cardona, Tarun Mahajan, Qi Wen Teo, Jassir Páez, Joseph Lederer, Jie Chen, Nicholas C. Wu, Sergei Maslov, Christopher B. Brooke

The paper shows that single-cell heterogeneity in IFN induction potential is heritable and driven by baseline variation in JNK and AP-1 signaling states.

Cell Systems · Jul 16, 2026Peer-reviewedSystems Biology

Intrinsic OASL expression licenses interferon induction during influenza A virus infection

Joel Rivera-Cardona, Tarun Mahajan, Neeha Kakuturu, Qi Wen Teo, Joseph Lederer, Elizabeth A. Thayer, Elizabeth F. Rowland, Kyle Heimburger, Jiayi Sun, Cera A. McDonald, Clayton K. Mickelson, Ryan Andrew Langlois, Nicholas C. Wu, Olgica Milenković, Sergei Maslov, Christopher B. Brooke

The paper identifies intrinsic OASL expression as a determinant of IFN induction potential in influenza A virus-infected cells using scRNA-seq analysis.

bioRxiv · Mar 14, 2025 · PreprintImmunology