Elizabeth A. Thayer

Single-cell heterogeneity in interferon induction potential is heritable and governed by variation in cell state

The paper shows that single-cell heterogeneity in IFN induction potential is heritable and driven by baseline variation in JNK and AP-1 signaling states.

Intrinsic OASL expression licenses interferon induction during influenza A virus infection

The paper identifies intrinsic OASL expression as a determinant of IFN induction potential in influenza A virus-infected cells using scRNA-seq analysis.

Seasonal influenza A virus lineages exhibit divergent abilities to antagonize interferon induction and signaling

This study compares the ability of seasonal H1N1 and H3N2 influenza A viruses to antagonize interferon induction and signaling at the single-cell level, finding differences in their IFN antagonism potential.