Novel compounds derived from AR-12 that demonstrate host-directed clearance of intracellular Salmonella enterica Serovar Typhimurium
Elizabeth G. Graham-Gurysh, M. Shamim Hasan Zahid, Devika M. Varma, Antonio Landavazo, Ojas A. Namjoshi, Joseph W. Wilson, Monica M. Johnson, Ryan N. Woodring, Aaron T. Hendricksen, Joseph F. Vath, Erica N. Pino, Eric M. Bachelder, Bruce E. Blough, Kristy M. Ainslie
This paper develops AR-12 analogs that show improved host-directed clearance of intracellular Salmonella Typhimurium compared to the parent compound.
bioRxiv · May 22, 2026 · PreprintMicrobiology