Baiyi Quan

This paper introduces SLIM, a method for unbiased genome reduction in diverse bacteria, and demonstrates its application in Escherichia coli and other species.

This study identifies ENAH as an interactor of the HTT1a PRD and shows that EVH1 domain binding modulates HTT1a aggregation and fibril remodeling.

The paper shows proteomic asymmetry in mouse and human embryos that influences lineage segregation.

The paper identifies cold-sensitive protein conformational changes across the proteome using mass spectrometry in E. coli.

The paper screens 343 AR-12 analogs to identify host-directed anti-leishmanial compounds, finding four lead compounds with broad in vitro efficacy and a lysozyme-mediated mechanism.

This study introduces PhaseID, a method to identify protein components in LLPS condensates formed by IDRs, revealing how LLPS tunes interaction selectivity and enables new cellular functions.

This study shows that the gut microbiome increases mitochondrial respiration and oxidative stress in the brain of a Parkinson's disease mouse model, worsening motor symptoms.

The paper identifies regulatory elements and transcription factors in E. coli genes across diverse environments using experimental and computational methods.

This study investigates the distinct roles of VDAC1, VDAC2, and VDAC3 in mitochondrial respiration and cancer cell metabolism through isoform-specific knockouts in HeLa cells.