Author

Joshua S Bloom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 4 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:yeast· 4 Approach:experimental assay· 3 Approach:statistical model· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Leonid KruglyakiD· 5 shared Sebastian Treusch· 3 shared Frank W Albert· 2 shared Meru J Sadhu· 2 shared Arthur H Shockley· 1 shared Aylia Mohammadi· 1 shared Frank Albert· 1 shared Iulia E Kotenko· 1 shared

Activity by Year

2013-2016 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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5 shared papersGenetics

Leonid KruglyakORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

CRISPR-directed mitotic recombination enables genetic mapping without crosses

Meru J Sadhu, Joshua S Bloom, Laura Day, Leonid Kruglyak

This study uses CRISPR to create targeted recombination events in yeast, enabling fine-mapping of trait variation to a single causal polymorphism.

Science · May 27, 2016Peer-reviewedGenetics

Genetic interactions contribute less than additive effects to quantitative trait variation in yeast

Joshua S Bloom, Iulia Kotenko, Meru J Sadhu, Sebastian Treusch, Frank W Albert, Leonid Kruglyak

The paper estimates the contribution of genetic interactions to quantitative trait variation in yeast and finds they account for 9% of phenotypic variance, less than additive effects.

bioRxiv · Oct 8, 2015Genetics

Genetics of intra-species variation in avoidance behavior induced by a thermal stimulus in C. elegans

Rajarshi Ghosh, Joshua S Bloom, Aylia Mohammadi, Molly E Schumer, Peter Andolfatto, William S Ryu, Leonid Kruglyak

The paper identifies genetic loci influencing thermal avoidance behavior in C. elegans, showing how distinct genetic factors control different components of the response.

Genetics · Aug 1, 2015Peer-reviewedGenetics

Genetic dissection of MAPK-mediated complex traits across S. cerevisiae

Sebastian Treusch, Frank W Albert, Joshua S Bloom, Iulia E Kotenko, Leonid Kruglyak

This study identifies genetic variants influencing MAPK signaling phenotypes in S. cerevisiae using QTL mapping across diverse strains.

PLoS Genetics · Jan 8, 2015Peer-reviewedGenetics

Genetics of single-cell protein abundance variation in large yeast populations

Frank Albert, Sebastian Treusch, Arthur H Shockley, Joshua S Bloom, Leonid Kruglyak

The paper develops a method to identify genetic loci influencing protein abundance in yeast and finds more loci per gene than previous studies, with many loci affecting multiple proteins.

bioRxiv · Nov 7, 2013Genomics