ImmunologybioRxivPreprint
Secondary lymphoid organ endothelial cells prime alloreactive CD4+ T cells to trigger acute graft-versus-host disease
Haroon Shaikh, Pia Wittmann, Moutaz Helal…·Andreas Beilhack
This study identifies blood endothelial cells in secondary lymphoid organs as key APCs that prime donor CD4 T cells, leading to acute graft-versus-host disease.
DOI 10.1101/2025.10.07.677751