Author

Moutaz Helal

Universitätsklinikum WürzburgORCID 0000-0002-9561-1669Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Angela RiedeliD· 2 shared Hermann EinseleiD· 2 shared Alma ZerneckeiD· 1 shared Andreas BeilhackiD· 1 shared Angelika Wolf· 1 shared Annika Hofmann· 1 shared Antoine‐Emmanuel SalibaiD· 1 shared Arpa AintablianiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Angela RiedelORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 11, 2026

Profound CD4+ T-Cell Reprogramming by Melphalan-Driven Oxidative Stress in High-Risk Multiple Myeloma

Mara John, Nazia Afrin, Xiang Zhou…·Angela Riedel

This study shows that melphalan treatment causes oxidative stress in T cells, reducing CD4+ naive T cells in high-risk multiple myeloma patients.

DOI 10.64898/2026.06.08.730835

humanflow cytometry

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ImmunologybioRxivPreprintOct 7, 2025

Secondary lymphoid organ endothelial cells prime alloreactive CD4+ T cells to trigger acute graft-versus-host disease

Haroon Shaikh, Pia Wittmann, Moutaz Helal…·Andreas Beilhack

This study identifies blood endothelial cells in secondary lymphoid organs as key APCs that prime donor CD4 T cells, leading to acute graft-versus-host disease.

DOI 10.1101/2025.10.07.677751

mouseexperimental assay

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