Author

Judith Müller

Max Planck Institute of BiochemistryPrimary ORCID profile (0000-0001-6312-4893 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Judith MülleriD2 papers · Ludwig-Maximilians-Universität München

Biology Disciplines

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Biochemistry· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:fungi (other)· 1

Frequent Co-Authors

Alina S. ThieleniD· 2 shared Brenda Arlene SchulmaniD· 2 shared Peter J. MurrayiD· 2 shared Anna V. GrasseiD· 1 shared Bastian BräuningiD· 1 shared Benoit J. Van den EyndeiD· 1 shared Camille GuyotiD· 1 shared Claudia Strasser· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBiochemistry

Alina S. ThielenORCID

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3 papers

Recent·Most cited

Cysteine availability tunes ubiquitin signaling via inverse stability of LRRC58 E3 ligase and its substrate CDO1

Gisele A. Andree, Luca J. Stier, Kerstin Schmiederer, Alina S. Thielen, Luis Schmid, Samuel A. Maiwald, Karthik V. Gottemukkala, Jiale Du, Susanne von Gronau, Claudia Strasser, Judith Müller, Lukas T. Henneberg, Camille Guyot, Gary Kleiger, Matthias Mann, , Brenda Arlene Schulman

The paper identifies LRRC58 as a cysteine-responsive E3 ligase that regulates CDO1 stability via ubiquitylation, revealing a mechanism linking cysteine availability to proteasomal turnover.

Nature Communications · May 7, 2026Peer-reviewedBiochemistry

A CK2-FBXW11 kinase-E3 ubiquitin ligase cascade is a metabolic sensor regulating Tryptophan 2,3-dioxygenase stability

Alina S. Thielen, Bastian Bräuning, Karthik V Gottemukkala, Judith Müller, Jesuraj Rajan Prabu, Simon Klaessens, Benoit J. Van den Eynde, Peter J. Murray, Brenda Arlene Schulman

The paper identifies a CK2-FBXW11 kinase-E3 ubiquitin ligase cascade that regulates TDO2 stability through Trp-dependent phosphorylation shielding.

bioRxiv · Jan 12, 2026 · PreprintBiochemistry

Frequent horizontal chromosome transfer between asexual fungal insect pathogens

Michael Habig, Anna V. Grasse, Judith Müller, Eva H. Stukenbrock, Hanna Leitner, Sylvia Cremer

This study demonstrates frequent horizontal transfer of accessory chromosomes between strains and species of the fungus Metarhizium robertsii during co-infection, revealing it as a common mechanism for gene exchange in eukaryotic pathogens.

Proceedings of the National Academy of Sciences · Mar 5, 2024Peer-reviewedGenomics