Author
Max Planck Institute of Biochemistry
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
7 papers
Recent·Most cited
Sara Sepic, Karthik V Gottemukkala, Jiale Du…·Brenda Arlene Schulman
This study reveals how MKLN1's discoidin and Kelch domains recognize diverse degrons through multivalent interactions, enabling substrate recruitment by the CTLH-MKLN1 E3 ligase.
Frank Adolf, Ellen A. Goodall, Ekampreet Singh…·Brenda Arlene Schulman
This study reveals how FBXO7 and PI31 regulate the proteasome 20S core particle and how disease variants disrupt this function.
Gisele A. Andree, Luca J. Stier, Kerstin Schmiederer…·Brenda Arlene Schulman
The paper identifies LRRC58 as a cysteine-responsive E3 ligase that regulates CDO1 stability via ubiquitylation, revealing a mechanism linking cysteine availability to proteasomal turnover.
Jakob Farnung, Elena Slobodyanyuk, Peter Y. Wang…·David P. Bartel
This paper identifies how a human AGO-miRNA-trigger complex binds ZSWIM8 for CUL3-mediated polyubiquitylation, leading to target-directed miRNA degradation.
Carolin J. Klose, Jesuraj Rajan Prabu, Emma J. Fenech…·Matthias Johannes Feige
The paper presents a cryo-EM structure of the EMC:Spf1 supercomplex, showing how it integrates TMD insertion and dislocation activities for membrane protein quality control.
Frank Adolf, Jiale Du, Ellen A. Goodall…·Brenda Arlene Schulman
The paper uses cryo-EM to visualize the assembly of the human 20S proteasome, revealing how chaperones and propeptides guide subunit incorporation and proteasome activation.
Shuai Qiao, Christine Langlois, Jakub Chrustowicz…·Brenda Arlene Schulman
The paper reveals how environmental changes trigger structural transitions in GID E3 ubiquitin ligase complexes, enabling substrate recognition and degradation.