Author

Julia K. Ryan

Dana-Farber Cancer Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Eric S. FischeriD· 2 shared Katherine A. DonovaniD· 2 shared Kheewoong BaekiD· 2 shared Nathanael S. GrayiD· 2 shared Abby M. Thornhill· 1 shared Alyssa L. VeranoiD· 1 shared Anna M. SchmokeriD· 1 shared Benjamin L. EbertiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Eric S. FischerORCID

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Author profile →

2 papers

Recent·Most cited

Development of Degraders and 2-pyridinecarboxyaldehyde (2-PCA) as a recruitment Ligand for FBXO22

Tian Qiu, Zhe Zhuang, Woong Sub Byun, Zuzanna Kozicka, Kheewoong Baek, Jianing Zhong, Abby M. Thornhill, Julia K. Ryan, Katherine A. Donovan, Eric S. Fischer, Benjamin L. Ebert, Nathanael S. Gray

This paper develops chemical probes for FBXO22, including a degrader and a recruitment ligand, to enable targeted protein degradation applications.

bioRxiv · Aug 19, 2025 · PreprintBiochemistry

Unveiling the hidden interactome of CRBN molecular glues with chemoproteomics

Kheewoong Baek, Rebecca J. Metivier, Shourya S. Roy Burman, Jonathan W. Bushman, Hojong Yoon, Ryan J. Lumpkin, Julia K. Ryan, Dinah M. Abeja, Megha Lakshminarayan, Hong Yue, Samuel Ojeda, Yuan Xiong, Jianwei Che, Alyssa L. Verano, Anna M. Schmoker, , Eric S. Fischer

The paper identifies 298 protein targets of CRBN-binding molecular glues using a high-throughput affinity purification mass spectrometry workflow and demonstrates a lead compound for the new target PPIL4.

Nature Communications · Jul 24, 2025Peer-reviewedCancer Biology