Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II
Srinivasan Rengachari, S. Schilbach, Thangavelu Kaliyappan, Jérôme Gouge, Kristina Žumer, Juliane Schwarz, Henning Urlaub, Christian Dienemann, Alessandro Vannini, Patrick Cramer
This study determines the structural basis of RNA polymerase II initiation at snRNA promoters using SNAPc, revealing its role in DNA opening and transcription initiation independent of TFIIE and TFIIH.
Nature Structural & Molecular Biology · Nov 24, 2022Peer-reviewedMolecular Biology