Both L-lactyl and D-lactyl enantiomers modify histones in mouse testis
Julie Manessier, Hassan Hijazi, Lisa Vizzini, Sabine Brugière, Marie Courçon, Christophe Masselon, Alberto de la Iglesia, Julie Cocquet, Delphine Pflieger
The paper identifies L- and D-lactylation on histones H3 and H4 in mouse testis using proteomics and shows site-specific enantiomer preferences.
Molecular & Cellular Proteomics · Jun 13, 2026Peer-reviewedBiochemistry