Author

Christophe Bruley

Centre National de la Recherche ScientifiqueORCID 0000-0003-2155-1234Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Anne-Marie HesseiD· 1 shared Baptiste BruléiD· 1 shared Delphine PfliegeriD· 1 shared Hassan HijaziiD· 1 shared Julie Manessier· 1 shared Karine MérienneiD· 1 shared Marie CourçoniD· 1 shared Ole Nørregaard JenseniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Anne-Marie HesseORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Proteome ResearchPeer-reviewedMar 31, 2025

Mind Your Spectra: Points to be Aware of when Validating the Identification of Isobaric Histone Peptidoforms

Hassan Hijazi, Julie Manessier, Sabine Brugière…·Delphine Pflieger

The paper identifies challenges in validating isobaric histone peptidoforms using mass spectrometry and proposes strategies to improve their identification.

3 citations

mouseproteomics

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BioinformaticsAnalytical ChemistryPeer-reviewedSep 24, 2020

Beyond target-decoy competition: stable validation of peptide and protein identifications in mass spectrometry-based discovery proteomics

Yohann Couté, Christophe Bruley, Thomas Bürger

The paper challenges the use of target-decoy competition for FDR control in proteomics and proposes a more stable alternative based on the Benjamini-Hochberg framework.

75 citations

proteomicsstatistical model

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