Hippocampal purinergic P2X7 receptor level is increased in Alzheimer's disease patients, and associated with amyloid and tau pathologies
Cinzia Maschio, Junlong Wang, Upasana Maheshwari, Annika Keller, Axel Rominger, Uwe Konietzko, Agneta K. Nordberg, Christoph Höck, Roger M. Nitsch, Ruiqing Ni
The paper examines increased P2X7R levels in Alzheimer's disease hippocampi, correlating with amyloid and tau pathologies, and identifies its potential as a neuroinflammation marker.
bioRxiv · Feb 28, 2024 · PreprintNeuroscience