Cinzia Maschio

Hippocampal mGluR5 levels are comparable in Alzheimer's and control brains, and divergently influenced by amyloid and tau in control brain

This study finds no difference in hippocampal mGluR5 levels between Alzheimer's and control brains, but shows amyloid and tau have opposing effects on mGluR5 in controls.

Hippocampal purinergic P2X7 receptor level is increased in Alzheimer's disease patients, and associated with amyloid and tau pathologies

The paper examines increased P2X7R levels in Alzheimer's disease hippocampi, correlating with amyloid and tau pathologies, and identifies its potential as a neuroinflammation marker.

Relationship between reactive astrocytes, by SMBT-1 imaging, with amyloid-beta, tau, glucose metabolism, and microgliosis in mouse models of Alzheimer's disease

Non-invasive imaging of tau-targeted probe uptake by whole brain multi-spectral optoacoustic tomography

This paper demonstrates non-invasive whole brain imaging of tau deposits using vMSOT and PBB5 probe in P301L mice, showing specific binding and retention in tau-laden regions.